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Repurposing a clinically approved prescription Colquhounia root tablet to treat diabetic kidney disease via suppressing PI3K/AKT/NF-kB activation

BACKGROUND: Growing clinical evidences show the potentials of Colquhounia root tablet (CRT) in alleviating diabetic kidney disease (DKD). However, its pharmacological properties and underlying mechanisms remain unclear. METHODS: ‘Drug target-Disease gene’ interaction network was constructed and the...

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Detalles Bibliográficos
Autores principales: Ma, Zhaochen, Liu, Yudong, Li, Congchong, Zhang, Yanqiong, Lin, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725443/
https://www.ncbi.nlm.nih.gov/pubmed/34980163
http://dx.doi.org/10.1186/s13020-021-00563-7