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Repurposing a clinically approved prescription Colquhounia root tablet to treat diabetic kidney disease via suppressing PI3K/AKT/NF-kB activation

BACKGROUND: Growing clinical evidences show the potentials of Colquhounia root tablet (CRT) in alleviating diabetic kidney disease (DKD). However, its pharmacological properties and underlying mechanisms remain unclear. METHODS: ‘Drug target-Disease gene’ interaction network was constructed and the...

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Detalles Bibliográficos
Autores principales:	Ma, Zhaochen, Liu, Yudong, Li, Congchong, Zhang, Yanqiong, Lin, Na
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725443/ https://www.ncbi.nlm.nih.gov/pubmed/34980163 http://dx.doi.org/10.1186/s13020-021-00563-7

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