SCUBE3 downregulation modulates hepatocellular carcinoma by inhibiting CCNE1 via TGFβ/PI3K/AKT/GSK3β pathway

OBJECTIVES: We aimed to verify the role of signal peptide-CUB-EGF-like domain-containing protein3 (SCUBE3) in the hepatocellular carcinoma (HCC) progression. METHODS: The role of SCUBE3 in HCC cell proliferation, apoptosis, and cell cycle in vitro were detected using MTT assay, colony formation assa...

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Detalles Bibliográficos
Autores principales: Xu, Pan, Luo, Aoran, Xiong, Chuan, Ren, Hong, Yan, Liang, Luo, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725472/
https://www.ncbi.nlm.nih.gov/pubmed/34980127
http://dx.doi.org/10.1186/s12935-021-02402-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725472/
https://www.ncbi.nlm.nih.gov/pubmed/34980127
http://dx.doi.org/10.1186/s12935-021-02402-z

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