Hypoxia increases expression of selected blood–brain barrier transporters GLUT-1, P-gp, SLC7A5 and TFRC, while maintaining barrier integrity, in brain capillary endothelial monolayers

BACKGROUND: Brain capillary endothelial cells (BCECs) experience hypoxic conditions during early brain development. The newly formed capillaries are tight and functional before astrocytes and pericytes join the capillaries and establish the neurovascular unit. Brain endothelial cell phenotype marker...

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Detalles Bibliográficos
Autores principales: Ozgür, Burak, Helms, Hans Christian Cederberg, Tornabene, Erica, Brodin, Birger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725498/
https://www.ncbi.nlm.nih.gov/pubmed/34983574
http://dx.doi.org/10.1186/s12987-021-00297-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725498/
https://www.ncbi.nlm.nih.gov/pubmed/34983574
http://dx.doi.org/10.1186/s12987-021-00297-6

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