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Turning the tide on Alzheimer’s disease: modulation of γ-secretase

Alzheimer’s disease (AD) is the most common type of neurodegenerative disorder. Amyloid-beta (Aβ) plaques are integral to the “amyloid hypothesis,” which states that the accumulation of Aβ peptides triggers a cascade of pathological events leading to neurodegeneration and ultimately AD. While the FD...

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Detalles Bibliográficos
Autores principales: Luo, Joanna E., Li, Yue-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725520/
https://www.ncbi.nlm.nih.gov/pubmed/34983641
http://dx.doi.org/10.1186/s13578-021-00738-7