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Turning the tide on Alzheimer’s disease: modulation of γ-secretase
Alzheimer’s disease (AD) is the most common type of neurodegenerative disorder. Amyloid-beta (Aβ) plaques are integral to the “amyloid hypothesis,” which states that the accumulation of Aβ peptides triggers a cascade of pathological events leading to neurodegeneration and ultimately AD. While the FD...
Autores principales: | Luo, Joanna E., Li, Yue-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725520/ https://www.ncbi.nlm.nih.gov/pubmed/34983641 http://dx.doi.org/10.1186/s13578-021-00738-7 |
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