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An ontogenic study of receptor mechanisms by which acute administration of low-doses of methamphetamine suppresses DOI-induced 5-HT(2A)-receptor mediated head-twitch response in mice

BACKGROUND: Methamphetamine (MA) is a non-selective monoamine releaser and thus releases serotonin (5-HT), norepinephrine (NE) and dopamine (DA) from corresponding nerve terminals into synapses. DOI ((±)-2, 5-dimethoxy-4-iodoamphetamine) is a direct-acting serotonergic 5-HT(2A/C) receptor agonist an...

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Detalles Bibliográficos
Autores principales: Sun, Yina, Chebolu, Seetha, Henry, Denise, Lankireddy, Sandeep, Darmani, Nissar A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725525/
https://www.ncbi.nlm.nih.gov/pubmed/34983399
http://dx.doi.org/10.1186/s12868-021-00686-5