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Assessment of NSAIDs as potential inhibitors of the fatty acid amide hydrolase I (FAAH-1) using three different primary fatty acid amide substrates in vitro

BACKGROUND: Pain relief remains a major subject of inadequately met need of patients. Therapeutic agents designed to treat pain and inflammation so far have low to moderate efficiencies with significant untoward side effects. FAAH-1 has been proposed as a promising target for the discovery of drugs...

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Detalles Bibliográficos
Autores principales: Dongdem, Julius T., Helegbe, Gideon K., Opare-Asamoah, Kwame, Wezena, Cletus A., Ocloo, Augustine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725537/
https://www.ncbi.nlm.nih.gov/pubmed/34983657
http://dx.doi.org/10.1186/s40360-021-00539-1