Cargando…

Development of a Spontaneous HPV16 E6/E7-Expressing Head and Neck Squamous Cell Carcinoma in HLA-A2 Transgenic Mice

Human papillomavirus (HPV)-associated head and neck squamous cell carcinoma (HNSCC) is a growing global health problem. HPV16 has been attributed to a majority of HPV-associated HNSCCs. In order to test candidate immunotherapies, we developed a spontaneous HPV16-driven HNSCC model in HLA-A2 (AAD) tr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Peng, Shiwen, Xing, Deyin, Ferrall, Louise, Tsai, Ya-Chea, Roden, Richard B. S., Hung, Chien-Fu, Wu, T.-C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725581/ https://www.ncbi.nlm.nih.gov/pubmed/35089069 http://dx.doi.org/10.1128/mbio.03252-21

Ejemplares similares

Erratum for Peng et al., “Development of a Spontaneous HPV16 E6/E7-Expressing Head and Neck Squamous Cell Carcinoma in HLA-A2 Transgenic Mice”
por: Peng, Shiwen, et al.
Publicado: (2022)

Identification of human MHC-I HPV18 E6/E7-specific CD8 + T cell epitopes and generation of an HPV18 E6/E7-expressing adenosquamous carcinoma in HLA-A2 transgenic mice
por: Peng, Shiwen, et al.
Publicado: (2022)

Control of Spontaneous HPV16 E6/E7 Expressing Oral Cancer in HLA-A2 (AAD) Transgenic Mice with Therapeutic HPV DNA Vaccine
por: Tseng, Ssu-Hsueh, et al.
Publicado: (2021)

Development of DNA Vaccine Targeting E6 and E7 Proteins of Human Papillomavirus 16 (HPV16) and HPV18 for Immunotherapy in Combination with Recombinant Vaccinia Boost and PD-1 Antibody
por: Peng, Shiwen, et al.
Publicado: (2021)

Immune responses, therapeutic anti-tumor effects, and tolerability upon therapeutic HPV16/18 E6/E7 DNA vaccination via needle-free biojector
por: Peng, Shiwen, et al.
Publicado: (2023)

Sequential Cisplatin Therapy and Vaccination with HPV16 E6E7L2 Fusion Protein in Saponin Adjuvant GPI-0100 for the Treatment of a Model HPV16+ Cancer
por: Peng, Shiwen, et al.
Publicado: (2015)

Induction of heparanase by HPV E6 oncogene in head and neck squamous cell carcinoma
por: Hirshoren, Nir, et al.
Publicado: (2014)

An Immunocompetent Mouse Model of HPV16(+) Head and Neck Squamous Cell Carcinoma
por: Carper, Miranda B., et al.
Publicado: (2019)

Targeting HPV16 E6-p300 interaction reactivates p53 and inhibits the tumorigenicity of HPV-positive head and neck squamous cell carcinoma
por: Xie, Xiujie, et al.
Publicado: (2013)

Interaction of HPV16 and Cutaneous HPV in Head and Neck Cancer
por: Al-Soneidar, Walid A., et al.
Publicado: (2022)

A HPV16-related prognostic indicator for head and neck squamous cell carcinoma
por: Zhang, Qian, et al.
Publicado: (2020)

Evaluation of HPV16 E7 expression in head and neck carcinoma cell lines and clinical specimens
por: Kitamura, Koji, et al.
Publicado: (2020)

Association of an intact E2 gene with higher HPV viral load, higher viral oncogene expression, and improved clinical outcome in HPV16 positive head and neck squamous cell carcinoma
por: Anayannis, Nicole V., et al.
Publicado: (2018)

HPV16 E6 enhances the radiosensitivity in HPV-positive human head and neck squamous cell carcinoma by regulating the miR-27a-3p/SMG1 axis
por: Long, Dan, et al.
Publicado: (2021)

Radiosensitization approaches for HPV‐positive and HPV‐negative head and neck squamous carcinomas
por: Dok, Rüveyda, et al.
Publicado: (2019)

The radiobiology of HPV-positive and HPV-negative head and neck squamous cell carcinoma
por: Zhou, Chumin, et al.
Publicado: (2020)

Author Correction: Evaluation of HPV16 E7 expression in head and neck carcinoma cell lines and clinical specimens
por: Kitamura, Koji, et al.
Publicado: (2021)

Exploring the roles of HPV16 variants in head and neck squamous cell carcinoma: current challenges and opportunities
por: Cochicho, Daniela, et al.
Publicado: (2021)

Development of a Novel Mouse Model of Spontaneous High-Risk HPVE6/E7–Expressing Carcinoma in the Cervicovaginal Tract
por: Henkle, Talia R., et al.
Publicado: (2021)

HPV16-E7-Specific Activated CD8 T Cells in E7 Transgenic Skin and Skin Grafts
por: Jazayeri, Seyed Davoud, et al.
Publicado: (2017)

Identification of novel HLA-A*11:01-restricted HPV16 E6/E7 epitopes and T-cell receptors for HPV-related cancer immunotherapy
por: Xiong, Chengjie, et al.
Publicado: (2022)

Radioimmunotherapy of experimental head and neck squamous cell carcinoma (HNSCC) with E6-specific antibody using a novel HPV-16 positive HNSCC cell line
por: Harris, Matthew, et al.
Publicado: (2011)

Innovative DNA Vaccine for Human Papillomavirus (HPV)-Associated Head and Neck Cancer
por: Wu, Annie, et al.
Publicado: (2010)

Radioimmunotherapy in HPV-Associated Head and Neck Squamous Cell Carcinoma
por: Zhou, Xin, et al.
Publicado: (2022)

Safety Run-in of Intramuscular pNGVL4a-Sig/E7(detox)/HSP70 DNA and TA-CIN Protein Vaccination as Treatment for HPV16+ ASC-US, ASC-H, or LSIL/CIN1
por: Einstein, Mark H., et al.
Publicado: (2023)

Regulation of HPV16 E6 and MCL1 by SF3B1 inhibitor in head and neck cancer cells
por: Gao, Yang, et al.
Publicado: (2014)

Characteristics and Impact of HPV-Associated p16 Expression on Head and Neck Squamous Cell Carcinoma in Thai Patients
por: Jiarpinitnun, Chuleeporn, et al.
Publicado: (2020)

Correction: Identification of novel HLA-A*11:01-restricted HPV16 E6/E7 epitopes and T-cell receptors for HPV-related cancer immunotherapy
Publicado: (2022)

Differences in the prognosis of HPV16-positive patients with squamous cell carcinoma of head and neck according to viral load and expression of P16
por: Biesaga, Beata, et al.
Publicado: (2017)

Virus-Like Particles Harboring CCL19, IL-2 and HPV16 E7 Elicit Protective T Cell Responses in HLA-A2 Transgenic Mice
por: Juarez, Victoria, et al.
Publicado: (2012)

Serum antibodies to the HPV16 proteome as biomarkers for head and neck cancer
por: Anderson, K S, et al.
Publicado: (2011)

EGFR-induced suppression of HPV E6/E7 is mediated by microRNA-9-5p silencing of BRD4 protein in HPV-positive head and neck squamous cell carcinoma
por: Nantajit, Danupon, et al.
Publicado: (2022)

Murine HPV16 E7-expressing transgenic skin effectively emulates the cellular and molecular features of human high-grade squamous intraepithelial lesions
por: Tuong, Z.K., et al.
Publicado: (2017)

Genetic variants of NOXA and MCL1 modify the risk of HPV16-associated squamous cell carcinoma of the head and neck
por: Zhou, Ziyuan, et al.
Publicado: (2012)

Advancements in the Management of HPV-Associated Head and Neck Squamous Cell Carcinoma
por: Zeitlin, Ross, et al.
Publicado: (2015)

HPV Detection in Head and Neck Squamous Cell Carcinomas: What Is the Issue?
por: Augustin, Jeremy Gbenakpon, et al.
Publicado: (2020)

Analysis of the anatomical distribution of HPV genotypes in head and neck squamous papillomas
por: Hu, Huiying, et al.
Publicado: (2023)

Association of HLA-DRB1, HLA-DQB1 Polymorphisms with HPV 16 E6 Variants among Young Cervical Cancer Patients in China
por: Hu, Yan, et al.
Publicado: (2017)

HPV16 E6-specific T cell response and HLA-A alleles are related to the prognosis of patients with cervical cancer
por: Cai, Hongchao, et al.
Publicado: (2021)

TMEM16A/ANO1 is differentially expressed in HPV-negative versus HPV-positive head and neck squamous cell carcinoma through promoter methylation
por: Dixit, Ronak, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_c07dkas3961oc7ibmrgh0rb3mk