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Design, synthesis, and biological evaluation of biotinylated colchicine derivatives as potential antitumor agents
Chemical drug design based on the biochemical characteristics of cancer cells has become an important strategy for discovering new anti-tumour drugs to improve tumour targeting effects and reduce off-target toxicities. Colchicine is one of the most prominent and historically microtubule-targeting dr...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725855/ https://www.ncbi.nlm.nih.gov/pubmed/34915785 http://dx.doi.org/10.1080/14756366.2021.2013832 |