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Design, synthesis, and biological evaluation of biotinylated colchicine derivatives as potential antitumor agents

Chemical drug design based on the biochemical characteristics of cancer cells has become an important strategy for discovering new anti-tumour drugs to improve tumour targeting effects and reduce off-target toxicities. Colchicine is one of the most prominent and historically microtubule-targeting dr...

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Detalles Bibliográficos
Autores principales:	Wang, Chao, Zhang, Yujing, Wang, Zeyu, Li, Yuelin, Guan, Qi, Xing, Dongming, Zhang, Weige
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725855/ https://www.ncbi.nlm.nih.gov/pubmed/34915785 http://dx.doi.org/10.1080/14756366.2021.2013832

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