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Development of a naringenin microemulsion as a prospective ophthalmic delivery system for the treatment of corneal neovascularization: in vitro and in vivo evaluation

Naringenin, a flavonoid, possesses antiangiogenic potential and inhibits corneal neovascularization (CNV); however, its therapeutic use is restricted due to poor solubility and limited bioavailability. In this study, we developed a naringenin microemulsion (NAR-ME) for inhibiting CNV. NAR-ME formula...

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Detalles Bibliográficos
Autores principales: Ma, Yu, Yang, Jingjing, Zhang, Yali, Zheng, Chunyan, Liang, Zhen, Lu, Ping, Song, Fei, Wang, Yuwei, Zhang, Junjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725867/
https://www.ncbi.nlm.nih.gov/pubmed/34964414
http://dx.doi.org/10.1080/10717544.2021.2021323