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Deciphering the molecular mechanism of tetrandrine in inhibiting hepatocellular carcinoma and increasing sorafenib sensitivity by combining network pharmacology and experimental evaluation

CONTEXT: The mechanism of tetrandrine (TET) in hepatocellular carcinoma (HCC) progression and sorafenib (Sora) chemosensitivity deserves investigation. OBJECTIVE: Using network pharmacology approaches to elucidate the mechanisms of TET in HCC. MATERIALS AND METHODS: CCK-8, colony formation, and flow...

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Detalles Bibliográficos
Autores principales: Niu, Biao, Wei, Sidong, Sun, Jianjun, Zhao, Huibo, Wang, Bing, Chen, Guoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725900/
https://www.ncbi.nlm.nih.gov/pubmed/34962429
http://dx.doi.org/10.1080/13880209.2021.2017468