1,3,4-Oxadiazole-naphthalene hybrids as potential VEGFR-2 inhibitors: design, synthesis, antiproliferative activity, apoptotic effect, and in silico studies

In the current work, some 1,3,4-oxadiazole-naphthalene hybrids were designed and synthesised as VEGFR-2 inhibitors. The synthesised compounds were evaluated in vitro for their antiproliferative activity against two human cancer cell lines namely, HepG-2 and MCF-7. Compounds that exhibited promising...

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Detalles Bibliográficos
Autores principales: Hagras, Mohamed, Saleh, Marwa A., Ezz Eldin, Rogy R., Abuelkhir, Abdelrahman A., Khidr, Emad Gamil, El-Husseiny, Ahmed A., El-Mahdy, Hesham A., Elkaeed, Eslam B., Eissa, Ibrahim H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725909/
https://www.ncbi.nlm.nih.gov/pubmed/34923885
http://dx.doi.org/10.1080/14756366.2021.2015342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725909/
https://www.ncbi.nlm.nih.gov/pubmed/34923885
http://dx.doi.org/10.1080/14756366.2021.2015342

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