Design, synthesis, and biological evaluation of new thieno[2,3-d] pyrimidine derivatives as targeted therapy for PI3K with molecular modelling study

Cancer is one of the most aggressive diseases characterised by abnormal growth and uncontrolled cell division. PI3K is a lipid kinase involved in cancer progression which makes it fruitful target for cancer control. 28 new morpholine based thieno[2,3-d] pyrimidine derivatives were designed and synth...

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Detalles Bibliográficos
Autores principales: Elmenier, Fatma M., Lasheen, Deena S., Abouzid, Khaled A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725920/
https://www.ncbi.nlm.nih.gov/pubmed/34955086
http://dx.doi.org/10.1080/14756366.2021.2010729

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725920/
https://www.ncbi.nlm.nih.gov/pubmed/34955086
http://dx.doi.org/10.1080/14756366.2021.2010729

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