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Fully automated expansion and activation of clinical-grade natural killer cells for adoptive immunotherapy

BACKGROUND AIMS. Ex vivo expansion of natural killer (NK) cells is a strategy to produce large numbers of these effector cells for immunotherapy. However, the transfer of bench-top expansion protocols to clinically applicable methods is challenging for NK cell–based therapy because of regulatory asp...

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Detalles Bibliográficos
Autores principales: GRANZIN, MARKUS, SOLTENBORN, STEPHANIE, MÜLLER, SABINE, KOLLET, JUTTA, BERG, MARIA, CERWENKA, ADELHEID, CHILDS, RICHARD W., HUPPERT, VOLKER
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725994/
https://www.ncbi.nlm.nih.gov/pubmed/25881519
http://dx.doi.org/10.1016/j.jcyt.2015.03.611