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WLS/wntless is essential in controlling dendritic cell homeostasis via a WNT signaling-independent mechanism

We propose that beyond its role in WNT secretion, WLS/GPR177 (wntless, WNT ligand secretion mediator) acts as an essential regulator controlling protein glycosylation, endoplasmic reticulum (ER) homeostasis, and dendritic cell (DC)-mediated immunity. WLS deficiency in bone marrow-derived DCs (BMDCs)...

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Detalles Bibliográficos
Autores principales: Wang, Li-Ting, Lin, Ming-Hong, Liu, Kwei-Yan, Chiou, Shyh-Shin, Wang, Shen-Nien, Chai, Chee-Yin, Tseng, Li-Wen, Chiou, Hsin-Ying Clair, Wang, Hsueh-Chun, Yokoyama, Kazunari K., Hsu, Shih-Hsien, Huang, Shau-Ku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8726611/
https://www.ncbi.nlm.nih.gov/pubmed/33853474
http://dx.doi.org/10.1080/15548627.2021.1907516