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Fc gamma receptor IIIb binding of individual antibody proteoforms resolved by affinity chromatography–mass spectrometry

The crystallizable fragment (Fc) of immunoglobulin G (IgG) activates key immunological responses by interacting with Fc gamma receptors (FcɣR). FcɣRIIIb contributes to neutrophil activation and is involved in antibody-dependent cellular cytotoxicity (ADCC) and antibody-dependent cellular phagocytosi...

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Detalles Bibliográficos
Autores principales: Lippold, Steffen, Knaupp, Alexander, de Ru, Arnoud H., Tjokrodirijo, Rayman T. N., van Veelen, Peter A., van Puijenbroek, Erwin, de Taeye, Steven W., Reusch, Dietmar, Vidarsson, Gestur, Wuhrer, Manfred, Schlothauer, Tilman, Falck, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8726612/
https://www.ncbi.nlm.nih.gov/pubmed/34674601
http://dx.doi.org/10.1080/19420862.2021.1982847