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Fc gamma receptor IIIb binding of individual antibody proteoforms resolved by affinity chromatography–mass spectrometry
The crystallizable fragment (Fc) of immunoglobulin G (IgG) activates key immunological responses by interacting with Fc gamma receptors (FcɣR). FcɣRIIIb contributes to neutrophil activation and is involved in antibody-dependent cellular cytotoxicity (ADCC) and antibody-dependent cellular phagocytosi...
Autores principales: | Lippold, Steffen, Knaupp, Alexander, de Ru, Arnoud H., Tjokrodirijo, Rayman T. N., van Veelen, Peter A., van Puijenbroek, Erwin, de Taeye, Steven W., Reusch, Dietmar, Vidarsson, Gestur, Wuhrer, Manfred, Schlothauer, Tilman, Falck, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8726612/ https://www.ncbi.nlm.nih.gov/pubmed/34674601 http://dx.doi.org/10.1080/19420862.2021.1982847 |
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