Loss-of-function SLC30A2 mutants are associated with gut dysbiosis and alterations in intestinal gene expression in preterm infants

Loss of Paneth cell (PC) function is implicated in intestinal dysbiosis, mucosal inflammation, and numerous intestinal disorders, including necrotizing enterocolitis (NEC). Studies in mouse models show that zinc transporter ZnT2 (SLC30A2) is critical for PC function, playing a role in granule format...

Descripción completa

Detalles Bibliográficos
Autores principales: Kelleher, Shannon L, Alam, Samina, Rivera, Olivia C, Barber-Zucker, Shiran, Zarivach, Raz, Wagatsuma, Takumi, Kambe, Taiho, Soybel, David I, Wright, Justin, Lamendella, Regina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8726655/
https://www.ncbi.nlm.nih.gov/pubmed/34965180
http://dx.doi.org/10.1080/19490976.2021.2014739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8726655/
https://www.ncbi.nlm.nih.gov/pubmed/34965180
http://dx.doi.org/10.1080/19490976.2021.2014739

Ejemplares similares