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Phenotypic whole-cell screening identifies a protective carbohydrate epitope on Klebsiella pneumoniae

The increasing global occurrence of recalcitrant multi-drug resistant Klebsiella pneumoniae infections warrants the investigation of alternative therapy options, such as the use of monoclonal antibodies (mAbs). We used a target-agnostic phage display approach to K. pneumoniae bacteria lacking bulky,...

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Detalles Bibliográficos
Autores principales: Berry, Sophia K., Rust, Steven, Caceres, Carolina, Irving, Lorraine, Bartholdson Scott, Josefin, Tabor, David E., Dougan, Gordon, Christie, Graham, Warrener, Paul, Minter, Ralph, Grant, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8726669/
https://www.ncbi.nlm.nih.gov/pubmed/34923908
http://dx.doi.org/10.1080/19420862.2021.2006123