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Deathly triangle for pancreatic β-cells: Hippo pathway-MTORC1-autophagy
A progressive decline in the macroautophagic/autophagic flux is a hallmark of pancreatic β-cell failure in type 2 diabetes (T2D) but the responsible intrinsic factors and underlying molecular mechanisms are incompletely understood. A stress-sensitive multicomponent cellular loop of the Hippo pathway...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8726679/ https://www.ncbi.nlm.nih.gov/pubmed/34470573 http://dx.doi.org/10.1080/15548627.2021.1972404 |