PRDX1 activates autophagy via the PTEN-AKT signaling pathway to protect against cisplatin-induced spiral ganglion neuron damage

Spiral ganglion neurons (SGNs) are auditory neurons that relay sound signals from the inner ear to the brainstem. The ototoxic drug cisplatin can damage SGNs and thus lead to sensorineural hearing loss (SNHL), and there are currently no methods for preventing or treating this. Macroautophagy/autopha...

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Detalles Bibliográficos
Autores principales: Liu, Wenwen, Xu, Lei, Wang, Xue, Zhang, Daogong, Sun, Gaoying, Wang, Man, Wang, Mingming, Han, Yuechen, Chai, Renjie, Wang, Haibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8726717/
https://www.ncbi.nlm.nih.gov/pubmed/33749526
http://dx.doi.org/10.1080/15548627.2021.1905466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8726717/
https://www.ncbi.nlm.nih.gov/pubmed/33749526
http://dx.doi.org/10.1080/15548627.2021.1905466

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