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LDB1-mediated transcriptional complexes are sensitive to islet stress

Excess nutrients and proinflammatory cytokines impart stresses on pancreatic islet β-cells that, if unchecked, can lead to cellular dysfunction and/or death. Among these stress-induced effects is loss of key β-cell transcriptional regulator mRNA and protein levels required for β-cell function. Previ...

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Detalles Bibliográficos
Autores principales: Liu, Yanping, Kepple, Jessica D., Shalev, Anath, S. Hunter, Chad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8726731/
https://www.ncbi.nlm.nih.gov/pubmed/34968409
http://dx.doi.org/10.1080/19382014.2021.2016028