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LDB1-mediated transcriptional complexes are sensitive to islet stress
Excess nutrients and proinflammatory cytokines impart stresses on pancreatic islet β-cells that, if unchecked, can lead to cellular dysfunction and/or death. Among these stress-induced effects is loss of key β-cell transcriptional regulator mRNA and protein levels required for β-cell function. Previ...
Autores principales: | Liu, Yanping, Kepple, Jessica D., Shalev, Anath, S. Hunter, Chad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8726731/ https://www.ncbi.nlm.nih.gov/pubmed/34968409 http://dx.doi.org/10.1080/19382014.2021.2016028 |
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