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Clostridioides difficile Toxin CDT Induces Cytotoxic Responses in Human Mucosal-Associated Invariant T (MAIT) Cells

Clostridioides difficile is the major cause of antibiotic-associated colitis (CDAC) with increasing prevalence in morbidity and mortality. Severity of CDAC has been attributed to hypervirulent C. difficile strains, which in addition to toxin A and B (TcdA, TcdB) produce the binary toxin C. difficile...

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Detalles Bibliográficos
Autores principales: Marquardt, Isabel, Jakob, Josefine, Scheibel, Jessica, Hofmann, Julia Danielle, Klawonn, Frank, Neumann-Schaal, Meina, Gerhard, Ralf, Bruder, Dunja, Jänsch, Lothar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727052/
https://www.ncbi.nlm.nih.gov/pubmed/34992584
http://dx.doi.org/10.3389/fmicb.2021.752549