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NGS Analysis of Clonality and Minimal Residual Disease in a Patient with Concurrent Richter's Transformation and CLL/SLL

B-cell lymphomas are neoplastic proliferations of clonal B lymphocytes. Clonality is generally determined by PCR amplification of VDJ rearrangements in the IgH heavy chain or VJ rearrangements in Igκ/Igλ light chain genes followed by capillary electrophoresis. More recently, next-generation sequenci...

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Detalles Bibliográficos
Autores principales: Kadkol, Shrihari S., Bland, Joshua, Kavanaugh, Ashley, Ni, Hongyu, Nehru, Vijeyaluxmi, Peace, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727142/
https://www.ncbi.nlm.nih.gov/pubmed/34992887
http://dx.doi.org/10.1155/2021/9740281