Urolithin a alleviates oxidative stress-induced senescence in nucleus pulposus-derived mesenchymal stem cells through SIRT1/PGC-1α pathway

BACKGROUND: In degenerative intervertebral disc (IVD), an unfavorable IVD environment leads to increased senescence of nucleus pulposus (NP)-derived mesenchymal stem cells (NPMSCs) and the inability to complete the differentiation from NPMSCs to NP cells, leading to further aggravation of IVD degene...

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Detalles Bibliográficos
Autores principales: Shi, Peng-Zhi, Wang, Jun-Wu, Wang, Ping-Chuan, Han, Bo, Lu, Xu-Hua, Ren, Yong-Xin, Feng, Xin-Min, Cheng, Xiao-Fei, Zhang, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Basic Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727228/
https://www.ncbi.nlm.nih.gov/pubmed/35069991
http://dx.doi.org/10.4252/wjsc.v13.i12.1928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727228/
https://www.ncbi.nlm.nih.gov/pubmed/35069991
http://dx.doi.org/10.4252/wjsc.v13.i12.1928

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