Dual targeting of the DNA damage response pathway and BCL-2 in diffuse large B-cell lymphoma

Standard chemotherapies for diffuse large B-cell lymphoma (DLBCL), based on the induction of exogenous DNA damage and oxidative stress, are often less effective in the presence of increased MYC and BCL-2 levels, especially in the case of double hit (DH) lymphomas harboring rearrangements of the MYC...

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Detalles Bibliográficos
Autores principales: Rossi, Alessandra, Orecchioni, Stefania, Falvo, Paolo, Tabanelli, Valentina, Baiardi, Elena, Agostinelli, Claudio, Melle, Federica, Motta, Giovanna, Calleri, Angelica, Fiori, Stefano, Corsini, Chiara, Casadei, Beatrice, Mazzara, Saveria, Vitolo, Umberto, Bertolini, Francesco, Zinzani, Pier Luigi, Alcalay, Myriam, Pelicci, Pier Giuseppe, Pileri, Stefano, Tarella, Corrado, Derenzini, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727301/
https://www.ncbi.nlm.nih.gov/pubmed/34304248
http://dx.doi.org/10.1038/s41375-021-01347-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727301/
https://www.ncbi.nlm.nih.gov/pubmed/34304248
http://dx.doi.org/10.1038/s41375-021-01347-6

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