Targeting LAG3/GAL-3 to overcome immunosuppression and enhance anti-tumor immune responses in multiple myeloma

Immune profiling in patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering multiple myeloma (SMM), and multiple myeloma (MM) provides the framework for developing novel immunotherapeutic strategies. Here, we demonstrate decreased CD4(+) Th cells, increased Treg and G-typ...

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Detalles Bibliográficos
Autores principales: Bae, Jooeun, Accardi, Fabrizio, Hideshima, Teru, Tai, Yu-Tzu, Prabhala, Rao, Shambley, Aaron, Wen, Kenneth, Rowell, Sean, Richardson, Paul G., Munshi, Nikhil C., Anderson, Kenneth C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727303/
https://www.ncbi.nlm.nih.gov/pubmed/34290359
http://dx.doi.org/10.1038/s41375-021-01301-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727303/
https://www.ncbi.nlm.nih.gov/pubmed/34290359
http://dx.doi.org/10.1038/s41375-021-01301-6

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