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Therapeutic Effect of IL-38 on Experimental Autoimmune Uveitis: Reprogrammed Immune Cell Landscape and Reduced Th17 Cell Pathogenicity

PURPOSE: The purpose of this study was to elucidate the effects of interleukin (IL)-38 on experimental autoimmune uveitis (EAU) and its underlying mechanisms. METHODS: Mice with EAU were treated with IL-38, and the retinas and cervical draining lymph nodes (CDLNs) were analyzed by flow cytometry. Si...

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Detalles Bibliográficos
Autores principales: Li, He, Zhu, Lei, Wang, Rong, Xie, Lihui, Chen, Yuxi, Duan, Runping, Liu, Xiuxing, Huang, Zhaohao, Chen, Binyao, Li, Zhaohuai, Wang, Xianggui, Su, Wenru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727319/
https://www.ncbi.nlm.nih.gov/pubmed/34967854
http://dx.doi.org/10.1167/iovs.62.15.31