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Proteasome α6 Subunit Negatively Regulates the JAK/STAT Pathway and Blood Cell Activation in Drosophila melanogaster

JAK/STAT signaling regulates central biological functions such as development, cell differentiation and immune responses. In Drosophila, misregulated JAK/STAT signaling in blood cells (hemocytes) induces their aberrant activation. Using mass spectrometry to analyze proteins associated with a negativ...

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Detalles Bibliográficos
Autores principales: Järvelä-Stölting, Mirva, Vesala, Laura, Maasdorp, Matthew K., Ciantar, Joanna, Rämet, Mika, Valanne, Susanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727353/
https://www.ncbi.nlm.nih.gov/pubmed/35003057
http://dx.doi.org/10.3389/fimmu.2021.729631