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Proteasome α6 Subunit Negatively Regulates the JAK/STAT Pathway and Blood Cell Activation in Drosophila melanogaster
JAK/STAT signaling regulates central biological functions such as development, cell differentiation and immune responses. In Drosophila, misregulated JAK/STAT signaling in blood cells (hemocytes) induces their aberrant activation. Using mass spectrometry to analyze proteins associated with a negativ...
Autores principales: | Järvelä-Stölting, Mirva, Vesala, Laura, Maasdorp, Matthew K., Ciantar, Joanna, Rämet, Mika, Valanne, Susanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727353/ https://www.ncbi.nlm.nih.gov/pubmed/35003057 http://dx.doi.org/10.3389/fimmu.2021.729631 |
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