Reduction in O-glycome induces differentially glycosylated CD44 to promote stemness and metastasis in pancreatic cancer

Aberrant protein glycosylation has been shown to contribute to aggressive cancer, including pancreatic cancer (PC). Emerging evidence has implicated the involvement of cancer stem cells (CSCs) in PC aggressiveness; however, the contribution of glycosylation on self-renewal properties and maintenance...

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Detalles Bibliográficos
Autores principales: Leon, Frank, Seshacharyulu, Parthasarathy, Nimmakalaya, Rama K., Chugh, Seema, Karmakar, Saswati, Nallasamy, Palanisamy, Vengoji, Raghupathy, Rachagani, Satyanarayana, Cox, Jesse L., Mallya, Kavita, Batra, Surinder K., Ponnusamy, Moorthy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727507/
https://www.ncbi.nlm.nih.gov/pubmed/34675409
http://dx.doi.org/10.1038/s41388-021-02047-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727507/
https://www.ncbi.nlm.nih.gov/pubmed/34675409
http://dx.doi.org/10.1038/s41388-021-02047-2

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