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Shankopathies in the Developing Brain in Autism Spectrum Disorders

The SHANK family of proteins play critical structural and functional roles in the postsynaptic density (PSD) at excitatory glutamatergic synapses. Through their multidomain structure they form a structural platform across the PSD for protein–protein interactions, as well as recruiting protein comple...

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Detalles Bibliográficos
Autores principales: Vyas, Yukti, Cheyne, Juliette E., Lee, Kevin, Jung, Yewon, Cheung, Pang Ying, Montgomery, Johanna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727517/
https://www.ncbi.nlm.nih.gov/pubmed/35002604
http://dx.doi.org/10.3389/fnins.2021.775431