A Haptoglobin Exon Copy Number Variant Associates With HIV-Associated Neurocognitive Impairment in European and African-Descent Populations

A common two-exon deletion distinguishes the gene encoding the free hemoglobin capturing protein—haptoglobin (HP)–into two alleles: HP1 and HP2. To evaluate the impact of this copy number variant (CNV) on neurocognitive impairment (NCI) in people living with HIV, we imputed this variant in 432 Europ...

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Detalles Bibliográficos
Autores principales: Bai, Haimeng, Kaur, Harpreet, Kallianpur, Asha R., Hulgan, Todd, Franklin, Donald R., Letendre, Scott L., Ellis, Ronald J., Bush, William S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727522/
https://www.ncbi.nlm.nih.gov/pubmed/35003209
http://dx.doi.org/10.3389/fgene.2021.756685

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727522/
https://www.ncbi.nlm.nih.gov/pubmed/35003209
http://dx.doi.org/10.3389/fgene.2021.756685

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