Toxicokinetics of Arenobufagin and its Cardiotoxicity Mechanism Exploration Based on Lipidomics and Proteomics Approaches in Rats

Arenobufagin (ArBu), one of the main active bufadienolides of toad venom with cardiotonic effect, analgesic effect, and outstanding anti-tumor potentiality, is also a potential cardiotoxic component. In the present study, the cardiac effect of ArBu and its underlying mechanism were explored by integ...

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Detalles Bibliográficos
Autores principales: Zhao, Lijuan, Han, Lingyu, Wei, Xiaolu, Zhou, Yanyan, Zhang, Yanqiong, Si, Nan, Wang, Hongjie, Yang, Jian, Bian, Baolin, Zhao, Haiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727535/
https://www.ncbi.nlm.nih.gov/pubmed/35002716
http://dx.doi.org/10.3389/fphar.2021.780016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727535/
https://www.ncbi.nlm.nih.gov/pubmed/35002716
http://dx.doi.org/10.3389/fphar.2021.780016

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