Inhibition of aberrant Hif1α activation delays intervertebral disc degeneration in adult mice

The intervertebral disc (IVD) is the largest avascular tissue. Hypoxia-inducible factors (HIFs) play essential roles in regulating cellular adaptation in the IVD under physiological conditions. Disc degeneration disease (DDD) is one of the leading causes of disability, and current therapies are inef...

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Detalles Bibliográficos
Autores principales: Wang, Zuqiang, Chen, Hangang, Tan, Qiaoyan, Huang, Junlan, Zhou, Siru, Luo, Fengtao, Zhang, Dali, Yang, Jing, Li, Can, Chen, Bo, Sun, Xianding, Kuang, Liang, Jiang, Wanling, Ni, Zhenhong, Wang, Quan, Chen, Shuai, Du, Xiaolan, Chen, Di, Deng, Chuxia, Yin, Liangjun, Chen, Lin, Xie, Yangli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727577/
https://www.ncbi.nlm.nih.gov/pubmed/34983922
http://dx.doi.org/10.1038/s41413-021-00165-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727577/
https://www.ncbi.nlm.nih.gov/pubmed/34983922
http://dx.doi.org/10.1038/s41413-021-00165-x

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