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DNA Methylation Profiles of Purified Cell Types in Bronchoalveolar Lavage: Applications for Mixed Cell Paediatric Pulmonary Studies

In epigenome-wide association studies analysing DNA methylation from samples containing multiple cell types, it is essential to adjust the analysis for cell type composition. One well established strategy for achieving this is reference-based cell type deconvolution, which relies on knowledge of the...

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Detalles Bibliográficos
Autores principales: Shanthikumar, Shivanthan, Neeland, Melanie R., Saffery, Richard, Ranganathan, Sarath C., Oshlack, Alicia, Maksimovic, Jovana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727592/
https://www.ncbi.nlm.nih.gov/pubmed/35003108
http://dx.doi.org/10.3389/fimmu.2021.788705