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Single-Molecule RNA Sequencing Reveals IFNγ-Induced Differential Expression of Immune Escape Genes in Merkel Cell Polyomavirus–Positive MCC Cell Lines

Merkel cell carcinoma (MCC) is a rare and highly aggressive cancer, which is mainly caused by genomic integration of the Merkel cell polyomavirus and subsequent expression of a truncated form of its large T antigen. The resulting primary tumor is known to be immunogenic and under constant pressure t...

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Detalles Bibliográficos
Autores principales: Sauerer, Tatjana, Lischer, Christopher, Weich, Adrian, Berking, Carola, Vera, Julio, Dörrie, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727593/
https://www.ncbi.nlm.nih.gov/pubmed/35003017
http://dx.doi.org/10.3389/fmicb.2021.785662