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Single-Molecule RNA Sequencing Reveals IFNγ-Induced Differential Expression of Immune Escape Genes in Merkel Cell Polyomavirus–Positive MCC Cell Lines
Merkel cell carcinoma (MCC) is a rare and highly aggressive cancer, which is mainly caused by genomic integration of the Merkel cell polyomavirus and subsequent expression of a truncated form of its large T antigen. The resulting primary tumor is known to be immunogenic and under constant pressure t...
Autores principales: | Sauerer, Tatjana, Lischer, Christopher, Weich, Adrian, Berking, Carola, Vera, Julio, Dörrie, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727593/ https://www.ncbi.nlm.nih.gov/pubmed/35003017 http://dx.doi.org/10.3389/fmicb.2021.785662 |
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