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Aspartate β-Hydroxylase (ASPH) Expression in Acute Myeloid Leukemia: A Potential Novel Therapeutic Target

BACKGROUND: Aspartate β-hydroxylase (ASPH) is an embryonic transmembrane protein aberrantly upregulated in cancer cells, associated with malignant transformation and, in some reports, with poor clinical prognosis. OBJECTIVE: To report the expression patterns of ASPH in acute myeloid leukemia (AML)....

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Detalles Bibliográficos
Autores principales: Holtzman, Noa G., Lebowitz, Michael S., Koka, Rima, Baer, Maria R., Malhotra, Kanam, Shahlaee, Amir, Ghanbari, Hossein A., Bentzen, Søren M., Emadi, Ashkan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727599/
https://www.ncbi.nlm.nih.gov/pubmed/35004304
http://dx.doi.org/10.3389/fonc.2021.783744