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METTL3 Is Suppressed by Circular RNA circMETTL3/miR-34c-3p Signaling and Limits the Tumor Growth and Metastasis in Triple Negative Breast Cancer

Despite N6-methyladenosine (m(6)A) is functionally important in various biological processes, its role in the underlying regulatory mechanism in TNBC are lacking. In this study, we investigate the pathological role and the underlying mechanism of the m(6)A methylated RNA level and its major methyltr...

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Detalles Bibliográficos
Autores principales: Ruan, Han-guang, Gu, Wen-chao, Xia, Wen, Gong, Yan, Zhou, Xue-liang, Chen, Wen-yan, Xiong, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727604/
https://www.ncbi.nlm.nih.gov/pubmed/35004298
http://dx.doi.org/10.3389/fonc.2021.778132