TCOF1 upregulation in triple-negative breast cancer promotes stemness and tumour growth and correlates with poor prognosis

BACKGROUND: Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer with poor prognosis. By performing multiomic profiling, we recently uncovered super-enhancer heterogeneity between breast cancer subtypes. Our data also revealed TCOF1 as a putative TNBC-specific super-enhance...

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Detalles Bibliográficos
Autores principales: Hu, Jianyang, Lai, Yuni, Huang, Hao, Ramakrishnan, Saravanan, Pan, Yilin, Ma, Victor W. S., Cheuk, Wah, So, Grace Y. K., He, Qingling, Geoffrey Lau, C., Zhang, Liang, Cho, William C. S., Chan, Kui Ming, Wang, Xin, Rebecca Chin, Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727631/
https://www.ncbi.nlm.nih.gov/pubmed/34718356
http://dx.doi.org/10.1038/s41416-021-01596-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727631/
https://www.ncbi.nlm.nih.gov/pubmed/34718356
http://dx.doi.org/10.1038/s41416-021-01596-3

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