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A multivariate modeling framework to quantify immune checkpoint context-dependent stimulation on T cells

Cells receive, and adjust to, various stimuli, which function as part of complex microenvironments forming their “context”. The possibility that a given context impacts the response to a given stimulus defines “context-dependency” and it explains large parts of the functional variability of physiopa...

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Detalles Bibliográficos
Autores principales: Karpf, Léa, Trichot, Coline, Faucheux, Lilith, Legbre, Iris, Grandclaudon, Maximilien, Lahoute, Charlotte, Mattoo, Hamid, Pasquier, Benoit, Soumelis, Vassili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727669/
https://www.ncbi.nlm.nih.gov/pubmed/34983927
http://dx.doi.org/10.1038/s41421-021-00352-4