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FLUID study: study protocol for an open-label, single-centre pilot study to investigate the efFect of Lemborexant on sleep management in Japanese sUbjects aged 50 years and older with Insomnia Disorder

INTRODUCTION: Bidirectional associations have been reported between sleep disturbance and both cognitive impairment, including Alzheimer’s disease and amyloid beta-peptide (Aβ) accumulation. These relationships can be explained by the glymphatic system, which acts as a garbage drainage system in the...

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Detalles Bibliográficos
Autores principales: Okada, Ippei, Iwamoto, Kunihiro, Miyata, Seiko, Fujimoto, Akihiro, Tanaka, Masaki, Amano, Manabu, Matsuyama, Nao, Taoka, Toshiaki, Naganawa, Shinji, Ozaki, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727681/
https://www.ncbi.nlm.nih.gov/pubmed/34836909
http://dx.doi.org/10.1136/bmjopen-2021-054885