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Engineering of Reductive Aminases for Asymmetric Synthesis of Enantiopure Rasagiline
Reductive aminases (RedAms) for the stereoselective amination of ketones represent an environmentally benign and economically viable alternative to transition metal–catalyzed asymmetric chemical synthesis. Here, we report two RedAms from Aspergillus calidoustus (AcRedAm) and bacteria (BaRedAm) with...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727753/ https://www.ncbi.nlm.nih.gov/pubmed/35004654 http://dx.doi.org/10.3389/fbioe.2021.798147 |