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Engineering of Reductive Aminases for Asymmetric Synthesis of Enantiopure Rasagiline

Reductive aminases (RedAms) for the stereoselective amination of ketones represent an environmentally benign and economically viable alternative to transition metal–catalyzed asymmetric chemical synthesis. Here, we report two RedAms from Aspergillus calidoustus (AcRedAm) and bacteria (BaRedAm) with...

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Detalles Bibliográficos
Autores principales:	Zhang, Kai, He, Yuanzhi, Zhu, Jiawei, Zhang, Qi, Tang, Luyao, Cui, Li, Feng, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727753/ https://www.ncbi.nlm.nih.gov/pubmed/35004654 http://dx.doi.org/10.3389/fbioe.2021.798147

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