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A nanocleaner specifically penetrates the blood‒brain barrier at lesions to clean toxic proteins and regulate inflammation in Alzheimer's disease

Insurmountable blood‒brain barrier (BBB) and complex pathological features are the key factors affecting the treatment of Alzheimer's disease (AD). Poor accumulation of drugs in lesion sites and undesired effectiveness of simply reducing Aβ deposition or TAU protein need to be resolved urgently...

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Detalles Bibliográficos
Autores principales: Lei, Ting, Yang, Zhihang, Xia, Xue, Chen, Yuxiu, Yang, Xiaotong, Xie, Rou, Tong, Fan, Wang, Xiaolin, Gao, Huile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727781/
https://www.ncbi.nlm.nih.gov/pubmed/35024324
http://dx.doi.org/10.1016/j.apsb.2021.04.022