Hepatotoxicity reports in the FDA adverse event reporting system database: A comparison of drugs that cause injury via mitochondrial or other mechanisms

Drug-induced liver injury (DILI) is a leading reason for preclinical safety attrition and post-market drug withdrawals. Drug-induced mitochondrial toxicity has been shown to play an essential role in various forms of DILI, especially in idiosyncratic liver injury. This study examined liver injury re...

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Detalles Bibliográficos
Autores principales: Rana, Payal, Aleo, Michael D., Wen, Xuerong, Kogut, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727782/
https://www.ncbi.nlm.nih.gov/pubmed/35024312
http://dx.doi.org/10.1016/j.apsb.2021.05.028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727782/
https://www.ncbi.nlm.nih.gov/pubmed/35024312
http://dx.doi.org/10.1016/j.apsb.2021.05.028

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